Antes del Diluvio (a.k.a. "Before the Flood") takes place in the year 2070, just twelve hours before the extinction of the last living creatures on Earth. Robots that now rule the Earth are determined to gather different kinds of DNA as long as it is still available so that they can eventually recreate life on other planets.
Each hour is played as one round. On your turn, you have four action points to draw DNA tiles from different bags, put them into their incubator, or move them from the incubator to your habitat. The tiles have different shapes and sizes and must be placed to fit the habitat or the incubator. Each round has a different objective which, if fulfilled, gets you victory points. After twelve rounds, the player with most victory points wins.