From publisher blurb:
Welcome to the second adventure in the SANTIAGO: A Myth of the Far Future adventure path for the D&D 4E! In this adventure, the heroes continue their hunt for the greatest outlaw of them all.
Belladonna, Nightshade and the Sargasso Rose brings the heroes into a deeper plot. Fresh from their meeting with the raconteur Stern on Port Étrange, the party sets course for the planet of Belladonna, where they hope to meet with Duncan Black and learn more about their ultimate quarry, Santiago. After their first encounter with the Democracy, they’ll finally meet the Sargasso Rose, whose information will prove invaluable as they continue their hunt and set them on a crash course for planets mysterious and people even more so.
The far future awaits as this far future AP blazes new trails across the galaxy!
(Terminology thing you'll see in stat-blocks: a burner is a laser pistol, a screecher is a sonic pistol, and a bludger fires real bullets).