From the back of the adventure:
Exploding Orcs!Orcs in need have aid entered Loudwater. Before anyone can help, the feverish and pox marked creatures explode into a pile of sickening puss. Worse yet, they have unwittingly infected the city's denizens. A cure must be found before the City of Grottos is consumed the strange and virulent epidemic that devours all it infects. Are you up to the task?
Epidemic is an adventure for the Dungeons & Dragons (3.5 Edition) game. It can either be played as a stand-alone adventure, or as part of the LGR - Legacy of the Green Regent campaign offered by the RPGA. Designed to challenge 3rd-level D&D heroes, this adventure is a race to find a cure to a deadly disease.
To use this adventure, a Dungeon Master also needs the Player's Handbook (D&D 3.5e), the Dungeon Master's Guide (D&D 3.5e) and the Monster Manual (D&D 3.5e). This adventure is set in the Forgotten Realms game world, and it may also be useful, but not necessary, to also have a copy of the Forgotten Realms Campaign Setting.