Formulon

"Formulon is designed for use in the teaching of basic inorganic chemistry to pupils aged roughly 13 to 16 years. The game package consists of a pack of 100 cards, plus a three-page instructional leaflet; 78 of the cards represent atoms or ions (H, O, etc.), 20 multipliers (two or three) while the remaining two are Mendeleef cards (jokers) that can be used to represent any other card except a multiplier. The basic idea of the game is that pupils have to use the cards to make up chemical formulas."

Taken from the book, A Handbook of Game Design, by Henry Ellington, Eric Addinall, and Fred Percival. Kogan Page, London: 1982.