From publisher blurb:
Myths of the Far Future is the overall title for EN Publishing's "sci-fi D&D" ruleset. It includes a default setting, but is also designed to allow you to create your own myths of the far future. Using the rules presented herein, you should find enough information to pay futuristic characters in any far future setting of your own making.
THIS IS THE D&D 4E VERSION OF THIS PRODUCT.
This book is designed to help you, as a player, design a character for use in the SANTIAGO: A Myth of the Far Future adventure path, as well as futuristic campaigns of your own.
Myths of the Far Future is D&D 4E "reskinned" - using exactly the same rules you're used to (with new classes and powers), you can achieve pitch-perfect sci-fi flavor just by paying attention to the vocabulary. You can use any D&D 4E content in conjunction with Myths of the Far Future, including races, classes, monsters, items, and more.
Join the hunt for Santiago in Mike Resnick's far future galaxy, or start a futuristic campaign of your own with this book and the companion Campaign Guide - the far future needs heroes, and the far future is up to you!