SpongeBob SquarePants featuring Nicktoons: Globs Of Doom is a video game; the fourth installament in the Nicktoons Unite! series. Characters from SpongeBob SquarePants, Danny Phantom, The Adventures of Jimmy Neutron: Boy Genius, Tak and the Power of Juju and Invader Zim appear.
One seemingly normal day, SpongeBob and Squidward were on their way to work when huge asteroids started raining down on Bikini Bottom. A huge drop of goo fell on Squidward, causing the top part of his face to turn orange and becomes a cyclops of sorts. He becomes a zombie, chasing SpongeBob around the perimeter of someone's house until Patrick intervenes. Jimmy Neutron then arrives to take them to the Mawgu lair. Soon, the gooey creatures spawning from the asteroids start taking over Bikini Bottom...
Source: Wikipedia, "SpongeBob SquarePants featuring Nicktoons: Globs of Doom", available under the CC-BY-SA License.