From the "About" page:
Synanthropes is a story game about representatives of the known sentient races of planet Earth: the Crows, the Rats, the Roaches, the Cane Toads, the Geckos, and the Raccoons. Collectively, they may be referred to as the Synanthropes.
Sometime in the future, somewhere between twenty-five and one hundred years from today, humanity disappeared, for reasons unknown. Some time after that, synanthropes—those animals who live in ecological niches that humans created—evolved, becoming intelligent communities in their own right, aware that they live in Humanity’s cast-off ruins.
You play representatives of these groups, each player from a different species, who are joining together on a scientific expedition. It’s the first major cross-species undertaking since the end of the Resource Wars: there is a building, a skyscraper in the center of an otherwise abandoned wasteland, which has never been explored by any of your people. Your mission is simple: make your way to the top, collecting information and any useful Human Artifacts which have survived these centuries, and maybe, if you’re lucky, an answer to the question which has haunted the Synanthropes for as long as they’ve realized that there was a civilization before them: Where did the Humans go, anyway?
But be warned... the peace among your species is a fragile thing and the Wars weren’t just about resources, but about utter cultural incompatibility as well. Your species are just different. Your mission is as much about trust as discovery, and if it’s a failure, then quicker tempers among your people may once again call for war.