Vermin (originally known as The Exterminator in North America) was released in the Silver series on July 10, 1980 with 500,000 units sold. It is a single-screen single-player game.
In Vermin, moles pop out of the ground and try to get into the player's garden. The player has to hit the moles with a hammer to keep them out of the garden.
Vermin was recreated in Game Boy Gallery and Game & Watch Gallery for Game Boy and Game & Watch Gallery 2 for Game Boy Color. In WarioWare, Inc.: Mega Microgame$!, there is a microgame called "Vermin" in which Wario has to whack a mole with a hammer. It was recreated as a DSiWare game that was released for Nintendo DSi on July 15, 2009 in Japan,[40][41] on April 5, 2010 in the United States[46] and on April 9 in Europe;[47] and for Nintendo 3DS on July 7, 2011 in Europe.[47] A Legend of Zelda-themed version is included in the Game & Watch: The Legend of Zelda edition as part of The Legend of Zelda: 35th Anniversary.
In the Super Smash Bros. series, Mr. Game & Watch has several attacks which has him hit opponents on either side with two hammers, referencing Vermin.
Source: Wikipedia, "List of Game & Watch games", available under the CC-BY-SA License.