Zombies vs. Wrestlers is the fourth game in the Army vs. Aliens series, with each game being playable on its own while also allowing for any faction in one game to be played against any faction in another or for multiple sets to be combined for team games or "last man standing" challenge matches.
As in the other games, Zombies vs. Wrestlers features two new asymmetric forces: zombies (lead by the necromancer) and wrestlers (lead by the Luchador). Each player takes one of the factions and rolls all nine dice. Taking turns, players then either attack the opponent or use a special power. Dice that are used are placed into the dice cup. If a player cannot attack or use a power, he instead "rallies", rolling the dice cup and simultaneously rerolling all of his dice still in play.
The zombie dice are unique in that they have no rank 4 unit, and instead have an additional rank 1 unit on their dice. However, they have several powers that revolve around gaining extra rank 1 units. The wrestlers have a more standard 123456 ranks, but have unique special powers involving "roll offs" and "tag team" plays.